a potent inhibitor of papain-like cysteine proteases
MENT is a potent inhibitor of papain-like cysteine proteases cathepsins K, L, and V in vitro. Inhibition stoichiometry (SI) and second-order association rate constants (ka) can be assessed using the fluorogenic substrate N-Cbz-Phe-Arg-methylcoumarin as described elsewhere (Irving et al., 2