De Nadie had a unique style that incorporated a blend of Mexican folk art and contemporary techniques. Her use of bold colors and symbolism was a nod to the traditional art forms of her culture, while also showcasing the modern influences that she had encountered. Her work was often likened to that of Frida Kahlo, another Mexican artist who had a significant impact on the art world.

De Nadie's artwork was not only visually stunning but also served as a call to action for women's rights and empowerment. Her pieces were thought-provoking and encouraged viewers to think critically about the issues facing women in Mexican society. Through her work, she gave a voice to those who were marginalized and oppressed, and her legacy continues to inspire artists and activists today.